1. Opening Lync 2010 client may produce the following error: "Please wait while windows configures Microsoft Lync 2010".
2. MSI Installer errors may appear in the System Event Log:
Workaround: Create a new folder named: “OCSetupDir” in the %SystemDrive% (Usually “C” drive).
Also, its recommended to review Microsoft release notes for new updates/service pack for Lync 2010 client.
Please note that changing the registry key value:
-> “CBF94811614C24742897713C2A8CF527” manually may not resolve this issue.
This updates may resolved the issue that described above, without the need to use this workaround.