OpenUp - Non-Paged CLR Host
Sasha Goldshtein and Alon Fliess have released a very interesting project called Non-Paged CLR Host to OpenUp, Microsoft open source competition.
This project is a custom CLR host that can provide significant performance improvements for applications that consume large amounts of memory. This is accomplished by locking all CLR-allocated pages into physical memory. Running an application under this host can guarantee that paging will not occur even if other applications on the system are allocating and deallocating memory continuously, or if the application becomes idle for a long period of time.
Thanks Sasha and Alon!